General Considerations -

1. Injection methods vary depending on vascular access, differential diagnosis, and imaging examination type
2. The mode and method of delivery, either by hand or by power injector, also vary by procedure
3. Stable intravenous (IV) access is necessary
4. Referring to approved package inserts may be appropriate in determining contrast media doses and concentrations

5. It is important to avoid prolonged admixture of blood and contrast media in syringes and catheters whenever possible due to the risk of clot formation
6. In general, unless known to be safe, the admixture of contrast media and any medication should be avoided

Reference

ACR Manual on Contrast Media 2021